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Glycoside hydrolase family 92 : ウィキペディア英語版 | Glycoside hydrolase family 92
In molecular biology, glycoside hydrolase family 92 is a family of glycoside hydrolases. Glycoside hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.〔(Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999. )〕 This classification is available on the CAZy(http://www.cazy.org/GH1.html) web site,〔(Henrissat, B. and Coutinho P.M. "Carbohydrate-Active Enzymes server". 1999. )〕 and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.〔(CAZypedia, an online encyclopedia of carbohydrate-active enzymes. )〕 This domain occurs within alpha-1,2-mannosidases, which remove alpha-1,2-linked mannose residues from Man(9)(GlcNAc)(2) by hydrolysis. They are critical for the maturation of N-linked oligosaccharides and ER-associated degradation. Glycoside hydrolase family 92 includes enzymes with mannosyl-oligosaccharide α-1,2-mannosidase , mannosyl-oligosaccharide α-1,3-mannosidase , mannosyl-oligosaccharide α-1,6-mannosidase , α-mannosidase , α-1,2-mannosidase , α-1,3-mannosidase and α-1,4-mannosidase activities. It includes enzymes critical for the maturation of N-linked oligosaccharides and ER-associated degradation.〔 ==References==
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